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Rabbit Anti-SHISA5/PE-Cy3 Conjugated antibody (bs-23909R-PE-Cy3)
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說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢(xún)價(jià)
產(chǎn)品編號(hào) bs-23909R-PE-Cy3
英文名稱(chēng) Rabbit Anti-SHISA5/PE-Cy3 Conjugated antibody
中文名稱(chēng) PE-Cy3標(biāo)記的SHISA5蛋白抗體
別    名 pProtein shisa 5; Putative NF kappa B activating protein 120; Putative NFkB activating protein 120; Scotin; Shisa homolog 5 (Xenopus laevis); SHSA5_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢(xún)價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 細(xì)胞生物  細(xì)胞凋亡  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) (predicted: Human, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 26kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SHISA5
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.05M PB, pH 7.5.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes a member of the shisa family. The encoded protein is localized to the endoplasmic reticulum, and together with p53 induces apoptosis in a caspase-dependent manner. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]

Function:
Can induce apoptosis in a caspase-dependent manner and plays a role in p53/TP53-dependent apoptosis.

Subunit:
Interacts with PDCD6; PDCD6 can stabilze SHISA5.

Subcellular Location:
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Nucleus membrane.

DISEASE:
Induced in a p53/TP53-dependent manner in response to cellular stress.

Database links:

Entrez Gene: 51246 Human

Omim: 607290 Human

SwissProt: Q8N114 Human

Unigene: 414579 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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