| 產(chǎn)品編號 | bs-23857R-BF488 |
| 英文名稱 | Rabbit Anti-TFF2/BF488 Conjugated antibody |
| 中文名稱 | BF488標(biāo)記的三葉肽因子2抗體 |
| 別 名 | Trefoil factor2; mSP; SP; Spasmolytic polypeptide; Spasmolysin; SML 1; SML1; spasmolytic protein 1; TFF 2; trefoil factor 2 (spasmolytic protein 1); TFF 2; TFF2_HUMAN; Trefoil factor 2; Trefoil factor 2 precursor. |
| 規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 細(xì)胞生物 信號轉(zhuǎn)導(dǎo) 生長因子和激素 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human, Mouse, (predicted: Rat, Pig, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 12/14kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human TFF2 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. The encoded protein inhibits gastric acid secretion. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. Function: Inhibits gastrointestinal motility and gastric acid secretion. Could function as a structural component of gastric mucus, possibly by stabilizing glycoproteins in the mucus gel through interactions with carbohydrate side chains (By similarity). Subcellular Location: Secreted. Tissue Specificity: Stomach. Similarity: Contains 2 P-type (trefoil) domains. Database links: Entrez Gene: 7032 Human Omim: 182590 Human SwissProt: Q03403 Human Unigene: 2979 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 三葉肽可能使黏膜凝膠產(chǎn)生更大的穩(wěn)定性,使胃黏膜對各種損傷因子的防御能力增強。三葉肽在誘導(dǎo)上皮修復(fù)上的直接作用,可用于許多胃腸道疾病。它作為輔助劑或取代皮質(zhì)類固醇或其他免疫抑制劑，在潰瘍病及炎癥性腸病的治療上可能是一個突破。 |
