產(chǎn)品編號(hào) | bs-20009R-PE-Cy3 |
英文名稱 | Rabbit Anti-PMCA3/PE-Cy3 Conjugated antibody |
中文名稱 | PE-Cy3標(biāo)記的ATP酶鈣離子轉(zhuǎn)運(yùn)蛋白PMCA3抗體 |
別 名 | ATP2B3; ATP2B3 protein; Calcium Pump PMCA3 ATPase; ATPase Ca++ transporting plasma membrane 3; Plasma membrane calcium ATPase 3; Plasma membrane calcium ATPase isoform 3; Plasma membrane calcium pump isoform 3; Plasma membrane calcium transporting ATPase 3; PMCA 3; PMCA3; PMCA3a; AT2B3_HUMAN. |
規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
說(shuō) 明 書(shū) | 100ul |
研究領(lǐng)域 | 腫瘤 細(xì)胞生物 神經(jīng)生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 轉(zhuǎn)運(yùn)蛋白 |
抗體來(lái)源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | |
產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 134kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human PMCA3 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: Plasma membrane-type Ca2+-ATPases (PMCAs) mediate the export of bivalent calcium ions from eukaryotic cells. As members of the P class of ion-motive ATPases, PMCAs are a functionally diverse group of proteins that are derived from alternatively spliced transcripts originating from four distinct genes, PMCA1, 2, 3, and 4. The expression of different PMCA isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, and with respect to the physiological needs of specific cell and tissue types. Spatial and temporal rates of resting intracellular Ca2+ concentrations and Ca2+ signaling in eukaryotic cells are dependent on the array of PMCA isoforms that are expressed in concert with the rate of Ca2+ export. PMCA3 expression is confined to brain and skeletal muscle. The PMCA4 gene is located on human chromosome 1q25 and is ubiquitously expressed. Function: Calcium Pump PMCA3 ATPase belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. Calcium Pump PMCA3 ATPase is the plasma membrane calcium ATPase isoform 3. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Isoform XE and isoform XB are the most abundant isoforms and are detected at low levels in brain and fetal skeletal muscle. The other isoforms are only found at lower levels and not in fetal tissues. Similarity: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily. Database links: Entrez Gene: 490 Human Entrez Gene: 491 Human Entrez Gene: 492 Human Entrez Gene: 493 Human SwissProt: P20020 Human SwissProt: P23634 Human SwissProt: Q01814 Human SwissProt: Q16720 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 西西大胆一级裸体A片 | 真实国产亂伦wwwhd | 91麻豆精品国产人妻一区二区三区 | 美女少妇裸体AA级一AA | 国产激情视频在线观看 | 麻豆91精品视频在线观看 | 丝袜视频综合久久久蜜桃 | 午夜福利插逼网大吊网 | 一交一性一色一伦一区二 | 国产精品无码一区二区桃花视频 | 中文字幕在线免费观看视频 | 东京热大乱交色色色一区二区三区 | 一级黄色片在线免费看 | 中文字幕亚洲精品乱无码 | 无码免费TV在线视频 | 欧美黑人又大又粗的特点 | 18 黄色视频在线观看 | 亚洲一区二区三区在线 | 日本无码中文字幕 | 又大又粗又硬又爽又黄毛片视频 | 国产精品人人妻人人爽30p | 欧–美–性–交–黄–片 | 国产精品无码一区二区毛片视频 | 美女扒穴给你看的香蕉网站 | 91久久精品无码一区二区三区 | 99精品乱码国产在线观看 | 高清无码在线视频播放 | 精品一区二区三区呻吟声 | 欧美日韩性爱爱视频 | 丰满岳乱妇一区二区三区 | 婷婷涩嫩草鲁丝久久午夜精品 | 免费黄色视频观看 | 国产真实乱了老女人视频 | 户外勾搭女人无套内谢 | 老熟妇高潮一区二区高清视频 | 四川妇女毛多水多A片 | 中文字字幕在线中文乱码 | 国产高潮A片一区二区 | 日本在线免费观看视频 | 东方av影库在线观看 |