產(chǎn)品編號 | bs-13536R-Cy7 |
英文名稱 | Rabbit Anti-GPR43/Cy7 Conjugated antibody |
中文名稱 | Cy7標記的G蛋白偶聯(lián)受體43抗體 |
別 名 | GPCR GPR43; FFA2R; Ffar2; FFAR2_HUMAN; free fatty acid activated receptor 2; Free fatty acid receptor 2; G protein coupled receptor 43; G protein-coupled receptor 43; G-protein coupled receptor 43; GPR 43; GPR43; GPCR 43. |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul |
研究領(lǐng)域 | 細胞生物 信號轉(zhuǎn)導(dǎo) G蛋白偶聯(lián)受體 G蛋白信號 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Mouse, (predicted: Human, Rat, ) |
產(chǎn)品應(yīng)用 |
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 31kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human GPR43 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: G protein-coupled receptors provide attractive targets for drug therapy due to the sheer size and diversity of ligands within this receptor family. G protein-coupled receptor (GPR) GPR41 and GPR43 are related members of a homologous family of orphan G protein-coupled receptors that are tandemly encoded at a single chromosomal locus in both humans and mice. GPR43 functions as a ligand for short chain fatty acids (SCFAs), notably acetate and propionate. Bacteria in the gut produce high concentrations of SCFAs, which are subsequently released in the bloodstream, where they exert cellular effects on blood leukocytes, including calcium release, ERK1/2 activation, and inhibition of cAMP accumulation. These effects indicate a role for GPR43 in the recruitment of leukocytes, particularly polymorphonuclear cells, to sites of bacterial infection. Function: Receptor for short chain fatty acids through a G(i)-protein-mediated inhibition of adenylyl cyclase and elevation of intracellular calcium. The rank order of potency for agonists of this receptor is acetate= propionate = butyrate > pentanoate = formate. Subcellular Location: Cell membrane. Tissue Specificity: Expressed at relatively high levels in peripheral blood leukocytes and, to lesser, extent, in spleen. Similarity: Belongs to the G-protein coupled receptor 1 family. Database links: Entrez Gene: 2867 Human Omim: 603823 Human SwissProt: O15552 Human Unigene: 248056 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
1、抗體溶解方法 | |
2、抗體修復(fù)方式 | |
3、常用試劑的配制 | |
4、免疫組化操作步驟 | |
5、免疫組化問題解答 | |
6、Western Blotting 操作步驟 | |
7、Western Blotting 問題解答 | |
8、關(guān)于肽鏈的設(shè)計 | |
9、多肽的溶解與保存 | |
10、酶標抗體效價測定程序 | |
| 污视频网站免费在线观看 | 欧美婬乱片A片AAA毛片地址 | 国产一级一级毛片 | 国产一级a毛一级a看免费视频黑人 | 国产中文字幕在线观看 | 北条麻妃一区二区三区四区五区 | 国产乱妇乱子在线播放视频国产 | 91精品国产综合久久久不卡98口 | 亚洲黄色视频在线播放 | 成人H精精一区二区无码 | 亚洲中文字幕乱码免费播放 | 女生粉嫩自慰网站 | 国产99在线观看 | 国产一级a毛一级a看免费观看 | 亚洲中熟老妇女久久竟 | 中国一级特黄真人高清aa大片 | 亚洲综合一区二区 | 国产女性无套 免费网站 | 四川妇搡BBBBB搡BBB | 欧美激情婬妇A片AAA毛多水多 | 成年人免费在线视频 | 天天爱天天做天天大综合 | 亚洲无码在线观看了 | 性欧美暴力猛交6gHD | 高清无码在线免费播放 | 精品老熟女视频一区二区 | 久久久 成人网站免费观看 99热成人精品热久久66 | 国产精品传媒无码成人猛烈 | 国产123区在线观看 午夜成人免费视频网站 | 国产麻豆性爱视频 | 农村乱子伦一区二区三区 | 影音先锋av在线资源 | 国产婬片一级A片AAA毛片AⅤ | 精品人妻互换一区二区三区免费 | 成人国产片女人爽到高潮免费 | 在线观看污视频网站 | 欧美肥老太婆乱码A片 | 成人AV第二区国产精品 | 中文字幕乱近親相姦视频中出恩施 | 无码人妻AⅤ一区二区三区A片一 |