產(chǎn)品編號 | bs-13246R-BF350 |
英文名稱 | Rabbit Anti-G gamma7/BF350 Conjugated antibody |
中文名稱 | BF350標(biāo)記的G蛋白偶聯(lián)受體γ7抗體 |
別 名 | FLJ00058; GBG7_HUMAN; Gng7; GNGT7; Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-7 subunit; Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7. |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul |
研究領(lǐng)域 | 腫瘤 細(xì)胞生物 信號轉(zhuǎn)導(dǎo) G蛋白偶聯(lián)受體 新陳代謝 G蛋白信號 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, Chicken, Cow, ) |
產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 7kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human G gamma7 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. Plays a role in the regulation of adenylyl cyclase signaling in certain regions of the brain. Plays a role in the formation or stabilzation of a G protein heterotrimer (G(olf) subunit alpha-beta-gamma-7) that is required for adenylyl cyclase activity in the striatum. Function: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. Plays a role in the regulation of adenylyl cyclase signaling in certain regions of the brain. Plays a role in the formation or stabilzation of a G protein heterotrimer (G(olf) subunit alpha-beta-gamma-7) that is required for adenylyl cyclase activity in the striatum (By similarity). Subunit: G proteins are composed of 3 units, alpha, beta and gamma. Subcellular Location: Cell membrane. Tissue Specificity: Expressed in a variety of tissues. Down-regulated in pancreatic and esophageal cancer. Similarity: Belongs to the G protein gamma family. Database links: UniProtKB/Swiss-Prot: O60262.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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