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Rabbit Anti-phospho-delta 1 Catenin (Tyr280)/Gold Conjugated antibody (bs-14262R-Gold)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-14262R-Gold
英文名稱 Rabbit Anti-phospho-delta 1 Catenin (Tyr280)/Gold Conjugated antibody
中文名稱 膠體金標記的磷酸化δ連環(huán)蛋白抗體
別    名 delta 1 Catenin (phospho Y280); p-delta 1 Catenin (phospho Y280); Cadherin associated Src substrate; Cadherin-associated Src substrate; CAS; Catenin (cadherin associated protein) delta 1; Catenin delta 1; Catenin delta-1; CTND1_HUMAN; CTNND 1; CTNND; CTNND1; KIAA0384; p120; P120 CAS; p120 catenin; P120 CTN; p120(cas); p120(ctn); P120CAS; P120CTN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
產(chǎn)品類型 磷酸化抗體 
研究領域 細胞生物  信號轉(zhuǎn)導  干細胞  轉(zhuǎn)錄調(diào)節(jié)因子  細胞骨架  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse,  (predicted: Human, Rat, Dog, Pig, Cow, Horse, )
產(chǎn)品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 106kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human delta 1 Catenin around the phosphorylation site of Tyr280
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
This gene encodes a member of the Armadillo protein family, which function in adhesion between cells and signal transduction. Multiple translation initiation codons and alternative splicing result in many different isoforms being translated. Not all of the full-length natures of the described transcript variants have been determined. Read-through transcription also exists between this gene and the neighboring upstream thioredoxin-related transmembrane protein 2 (TMX2) gene. [provided by RefSeq, Dec 2010]

Function:
Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway (By similarity). May associate with and regulate the cell adhesion properties of both C- and E-cadherins. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage.

Subcellular Location:
Cytoplasm. Nucleus. Cell membrane. Interaction with GLIS2 promotes nuclear translocation (By similarity). NANOS1 induces its translocation from sites of cell-cell contact to the cytoplasm.

Tissue Specificity:
Expressed in vascular endothelium.

Post-translational modifications:
Phosphorylated by protein-tyrosine kinases. Dephosphorylated by PTPRJ.

Similarity:
Belongs to the beta-catenin family.
Contains 10 ARM repeats.

Database links:

Entrez Gene: 1500 Human

Entrez Gene: 12388 Mouse

Entrez Gene: 311163 Rat

Omim: 601045 Human

SwissProt: O60716 Human

SwissProt: P30999 Mouse

Unigene: 166011 Human

Unigene: 35738 Mouse

Unigene: 9435 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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