| 產(chǎn)品編號 | bs-12217R-BF488 |
| 英文名稱 | Rabbit Anti-ZNF263/BF488 Conjugated antibody |
| 中文名稱 | BF488標(biāo)記的鋅指蛋白263抗體 |
| 別 名 | A8 51; C2 H2 type zinc finger protein; FLJ20216; HF.12; HZF3.1; KOX25; PP838; Zfp113; Zinc finger protein 3 (A8 51); Zinc finger protein 3; Zinc finger protein HF.12; Zinc finger protein KOX25; ZN263_HUMAN. |
| 規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 轉(zhuǎn)錄調(diào)節(jié)因子 鋅指蛋白 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 77kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from Human ZNF263 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. As a member of the krueppel C2H2-type zinc-finger protein family, ZNF263 (Zinc finger protein 263), also known as FPM315 or ZKSCAN12 (Zinc finger protein with KRAB and SCAN domains 12), is a 683 amino acid nuclear protein that contains nine C2H2-type zinc fingers, one KRAB domain and one SCAN box domain. ZNF263 acts as a transcriptional repressor in the nucleus and is expressed in various tissues including heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocyte. Function: Might play an important role in basic cellular processes as a transcriptional repressor. Subcellular Location: Nucleus. Tissue Specificity: Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocyte. Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 9 C2H2-type zinc fingers. Contains 1 KRAB domain. Contains 1 SCAN box domain. Database links: UniProtKB/Swiss-Prot: O14978.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
