產(chǎn)品編號 | bs-5855R-APC |
英文名稱 | Rabbit Anti-ADAM32/APC Conjugated antibody |
中文名稱 | APC標(biāo)記的去整合素樣金屬蛋白酶32抗體 |
別 名 | A disintegrin and metalloproteinase domain 32; ADA32_HUMAN; ADAM 32; Adam32; Disintegrin and metalloproteinase domain-containing protein 32. |
規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
說 明 書 | 100ul |
研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) 信號轉(zhuǎn)導(dǎo) 激酶和磷酸酶 細(xì)胞骨架 細(xì)胞外基質(zhì) 泛素 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Guinea Pig, ) |
產(chǎn)品應(yīng)用 | IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 68kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human ADAM32 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: ADAM32 was first discovered in a search for testis-specific proteinases. ADAM32 was identified in human, rat, mouse, macaque and chimp, and thus far has been found only in testis. In mice, ADAM32 is found on the sperm surface, where it may play a role in fertilization. ADAM32 is a member of the ADAMs family (A Disintegrin And Metalloproteinase), but does not contain the canonical HExxHxxxxH zinc-binding metalloproteinase catalytic site. The domain structure of the full length ADAM32 includes a signal sequence, propeptide domain, metalloproteinase-like domain, disintegrin-like domain, cys-rich domain, EGF-like domain, a short spacer region, then the transmembrane domain and a cytoplasmic domain. Like many of the reproductive-specific ADAMS, ADAM32 plays a non-enzymatic role, or (as is the case for ADAMs 1 & 2 (fertilin alpha and beta)), the protein acts in concert with a proteolytically active ADAM to process proteins. Little is known about interactions between ADAM32 and other ADAMs. Several different sequences for human ADAM32 are published; 787, 688, 649, 629, and 279 amino acids in length. The 688 amino acid form is identical to the 787 AA form until the EGF-like domain, and lacks the TM and cytoplasmic domains. The 649 AA form is likewise identical to the longer form, just to the start of the TM domain, and also lacks the TM and cytoplasmic domains. The 629 AA form has a deletion of 107 residues midway into the MP-like domain, and lacks the amino end of the disintegrin domain, but contains the rest of the domains found in the full-length ADAM32. The predicted masses for the different versions are 87.8, 76.9, 72.9, 70.9 and 32.1, respectively, for the 786, 688, 649, 629 and 279 AA forms. Function: May play a role in sperm development and fertilization This is a non-catalytic metalloprotease-like protein (By similarity) Subcellular Location: Membrane; Single-pass type I membrane protein (Potential). Tissue Specificity: Testis specific. Similarity: Contains 1 disintegrin domain. Contains 1 EGF-like domain. Contains 1 peptidase M12B domain. Database links: Entrez Gene: 203102 Human SwissProt: Q8TC27 Human Unigene: 521545 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 細(xì)胞外基質(zhì)蛋白 |
| 91精品少妇一区二区三区蜜桃臀 | 香港一级婬片A片AAA | 性欧美精品 A片大乳在线 | 麻豆视频在线播放 | 久久夜色撩人国产综合AV | 久久久久成人精品免费播放动漫 | 精品人妻一区二区三区线国色天 | 免费一级婬片A片高潮喷水 影音先锋AV无码男人专区 | 国産精品久久久久久久 | 国产人妻无码一区二区三区不卡 | 色五月婷婷丁香五月婷婷 | 中文字幕 日韩二区 | 夜夜春极品少妇操出白浆 | 海角社区少妇女邻居在线 | 免费一级A片毛毛片有声小说 | 国产美女裸体永久免费 | 免费不卡可以看的av毛片网站 | 多人做波多野结衣A片在线观看 | 亚洲成人av一区二区在线播放 | 波多野结衣中文字幕无码 | 免费观看黃色A片免费一本 孕妇性交久久xxxAV片 | 午夜福利插逼网大吊网 | 蜜桃Av噜噜一区二区三区四区 | 星空传媒精品黄色视频 | 亚洲午夜精品一区二区 | 国产一区精品在线观看 | 国产精品久久久AV | 黑屌婷婷一区二区 | 捆绑人妻性奴一区二区 | 毛毛久久久久XXXX | 精品国产Av无码久久久影音先锋 | 国产黄色视频在线观看播放 | 国产一级婬片AAAAAA片麻代 | 一本一道AV无码中文蜜桃 | 亚洲性爱视频在线观看 | 国产一区视频在线播放 | 大地资源国精产品视频 | 91人妻人人做人人爽九色 | 搡老女人老太婆澡老太婆 | 日韩在线视频免费 |