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Rabbit Anti-DGCR2/FITC Conjugated antibody (bs-8258R-FITC)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-8258R-FITC
英文名稱 Rabbit Anti-DGCR2/FITC Conjugated antibody
中文名稱 FITC標(biāo)記的DGCR2蛋白抗體
別    名 DGS C; DGS2; DiGeorge syndrome critical region gene 2; IDD; integral membrane protein DGCR2; LAN; SEZ 12.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 心血管  細(xì)胞生物  免疫學(xué)  神經(jīng)生物學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Cow, Rabbit, Zebrafish, xenopuslaevisorangutan)
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 59kDa
細(xì)胞定位 細(xì)胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DGCR2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The DGCR2 gene encodes a novel putative adhesion receptor protein, which may play a role in neural crest cells migration, a process which has been proposed to be altered in DiGeorge syndrome. Deletions of the 22q11.2 have been associated with a wide range of developmental defects (notably DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome and isolated conotruncal cardiac defects) classified under the acronym CATCH 22.

Function:
Putative adhesion receptor, that could be involved in cell-cell or cell-matrix interactions required for normal cell differentiation and migration.

Subcellular Location:
Membrane; Single pass type I membrane protein.

Tissue Specificity:
Predominantly expressed in brain, heart, lung and fetal kidney. Low levels in liver and adult kidney.

Similarity:
Contains 1 C-type lectin domain.
Contains 1 LDL-receptor class A domain.
Contains 1 VWFC domain.

Database links:
UniProtKB/Swiss-Prot: P98153.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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