產(chǎn)品編號 | bs-3577R-Gold |
英文名稱 | Rabbit Anti-DMT1/Gold Conjugated antibody |
中文名稱 | 膠體金標(biāo)記的金屬離子轉(zhuǎn)運(yùn)體1抗體 |
別 名 | DCT 1; DCT1; Divalent metal transporter 1; DMT 1; DMT1; Natural resistance associated macrophage protein 2; NRAMP 2; NRAMP2; NRAM2_HUMAN. |
規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
說 明 書 | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 腫瘤 免疫學(xué) 神經(jīng)生物學(xué) |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Human, Mouse, Rat, (predicted: Cow, ) |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 62kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human DMT1 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: DMT1 is a major transporter of ferrous iron from the intestinal lumen. DMT1 belongs to the family of NRAMP metal ion transporters which function in diverse organisms from bacteria to human. DMT1 (NRAMP2) transports metal ions at the plasma membrane of cells of both the duodenum and in peripheral tissues, and defective DMT1 causes anaemia. Function: Actin-bundling protein. May function in mitogen-activated protein kinase pathway. Subcellular Location: Cytoplasm. Tissue Specificity: Heart, brain, lung, skeletal muscle, and kidney. Post-translational modifications: Actin-bundling activity is abolished upon phosphorylation by cAMP-dependent protein kinase. Similarity: Belongs to the villin/gelsolin family. Contains 1 HP (headpiece) domain. Database links: Entrez Gene: 4891 Human Entrez Gene: 18174 Mouse Omim: 600523 Human SwissProt: P49281 Human SwissProt: P49282 Mouse Unigene: 505545 Human Unigene: 234608 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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