產(chǎn)品編號(hào) | bs-2659R-BF488 |
英文名稱(chēng) | Rabbit Anti-MARCO/BF488 Conjugated antibody |
中文名稱(chēng) | BF488標(biāo)記的巨噬細(xì)胞清道夫受體抗體 |
別 名 | Macrophage receptor MARCO; Marco; MARCO_HUMAN; Macrophage receptor with collagenous structure; SCARA2; Scavenger receptor class A member 2. |
規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買(mǎi) 大包裝/詢(xún)價(jià) |
說(shuō) 明 書(shū) | 100ul |
研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 微生物學(xué) 細(xì)菌及病毒 |
抗體來(lái)源 | Rabbit |
克隆類(lèi)型 | Polyclonal |
交叉反應(yīng) | Mouse, (predicted: Human, Rat, Chicken, Dog, Guinea Pig, ,G) |
產(chǎn)品應(yīng)用 | IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 53kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human MARCO |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: The protein encoded by this gene is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains. [provided by RefSeq]. Function: Pattern recognition receptor (PRR). Binds Gram-positive and Gram-negative bacteria. Subunit: Homotrimer. Trimers may assemble in larger oligomers thus resulting in the creation of a large surface capable of interacting with very large ligands. Subcellular Location: Membrane; Single-pass type II membrane protein. Similarity: Contains 1 collagen-like domain. Contains 1 SRCR domain. Database links: Entrez Gene: 8685 Human Omim: 604870 Human SwissProt: Q9UEW3 Human Unigene: 67726 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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