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Rabbit Anti-IL3R alpha/Gold Conjugated antibody (bs-2600R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-2600R-Gold
英文名稱 Rabbit Anti-IL3R alpha/Gold Conjugated antibody
中文名稱 膠體金標(biāo)記的白介素3受體a鏈抗體
別    名 IL-3R alpha; IL3R alpha; Interleukin-3 receptor subunit alpha precursor; CD 123; CD123; CD123 antigen; hIL3Ra; IL 3 receptor subunit alpha; IL 3R alpha; IL 3R; IL 3R subunit alpha; IL3 receptor subunit alpha; IL3R alpha; IL3R; IL3RAY; IL3RX; IL3RY; Interleukin 3 receptor alpha; Interleukin 3 receptor, alpha (low affinity); Interleukin-3 receptor; MGC34174; IL3RA_HUMAN.   
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 細胞生物  免疫學(xué)  細胞膜受體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, 
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 40kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human IL-3R alpha
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found. [provided by RefSeq, Jun 2012]

Function:
This is a receptor for interleukin-3.

Subunit:
Heterodimer of an alpha and a beta subunit. The beta subunit is common to the IL3, IL5 and GM-CSF receptors.

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Similarity:
Belongs to the type I cytokine receptor family. Type 5 subfamily.

Database links:

Entrez Gene: 3563 Human

Omim: 308385 Human

Omim: 430000 Human

SwissProt: P26951 Human

Unigene: 632790 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

白細胞介素3受體α(IL-3Rα)又稱CD123,是造血生長因子受體家族成員,CD123是未分化白血病干細胞的特異標(biāo)志.在細胞信號轉(zhuǎn)導(dǎo)、細胞凋亡及血液腫瘤發(fā)生中起重要作用.
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