| 產(chǎn)品編號(hào) | bs-2456R-AP |
| 英文名稱 | Rabbit Anti-TNFSF18/AP Conjugated antibody |
| 中文名稱 | 堿性磷酸酶（AP）標(biāo)記的腫瘤壞死因子配體超家族成員18抗體 |
| 別 名 | Tumor necrosis factor ligand superfamily member 18; AITRL; GITRL; hGITRL; TL6; Activation inducible TNF related ligand; AITR ligand ; AITRL; GITR ligand; ; Glucocorticoid induced TNF related ligand; Glucocorticoid induced TNFR related protein ligand; MGC138237; Tumor necrosis factor (ligand) superfamily member 18; GITR Ligand; TNF18_HUMAN. |
| 規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 神經(jīng)生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 細(xì)胞凋亡 生長因子和激素 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Mouse, (predicted: Human, Rat, ) |
| 產(chǎn)品應(yīng)用 | WB=1:50-200 IHC-F=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 23kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human TNFSF18 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells. [provided by RefSeq]. Function: Cytokine that binds to TNFRSF18/AITR/GITR. Regulates T-cell responses. Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. Important for interactions between activated T-lymphocytes and endothelial cells. Mediates activation of NF-kappa-B. Subunit: Homodimer. Homotrimer. Subcellular Location: Cell membrane; Single-pass type II membrane protein. Tissue Specificity: Expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells. Similarity: Belongs to the tumor necrosis factor family. Database links: Entrez Gene: 8995 Human Entrez Gene: 240873 Mouse Omim: 603898 Human SwissProt: Q9UNG2 Human SwissProt: Q7TS55 Mouse Unigene: 248197 Human Unigene: 276823 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
