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Rabbit Anti-PTPRD/BF488 Conjugated antibody (bs-11471R-BF488)
訂購熱線:400-901-9800
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-11471R-BF488
英文名稱 Rabbit Anti-PTPRD/BF488 Conjugated antibody
中文名稱 BF488標記的酪氨酸磷酸酶PTPδ抗體 蛋白酪氨酸磷酸酶D受體抗體
別    名 protein tyrosine phosphatase receptor type D; RPTP Delta; Tyrosine phosphatase Delta; PTPRD_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  神經(jīng)生物學  信號轉(zhuǎn)導  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 212kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PTPRD (783-830aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
RelevancePTPRD is a protein tyrosine phosphatase that falls into the receptor-type group as it characteristically comprises an extracellular region, a single transmembrane region and two tandem cytoplasmic catalytic domains. The extracellular region of this protein contains 3 Ig-like and 8 fibronectin type III-like domains. This protein is thought to be involved in promoting neurite growth and in axonal guidance.

Subunit:
Interacts with IL1RAPL1 (via extracellular region); interaction is required for IL1RAPL1-mediated synapse formation (By similarity). Interacts with PPFIA1, PPFIA2 and PPFIA3.

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Post-translational modifications:
A cleavage occurs, separating the extracellular domain from the transmembrane segment. This process called 'ectodomain shedding' is thought to be involved in receptor desensitization, signal transduction and/or membrane localization.

Similarity:
Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily.
Contains 8 fibronectin type-III domains.
Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
Contains 2 tyrosine-protein phosphatase domains.

Database links:

Entrez Gene: 5789 Human

Omim: 601598 Human

SwissProt: P23468 Human

Unigene: 446083 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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