| 產(chǎn)品編號(hào) | bs-0629R-AP |
| 英文名稱 | Rabbit Anti-Estrogen Sulfotransferase/AP Conjugated antibody |
| 中文名稱 | 堿性磷酸酶（AP）標(biāo)記的雌激素硫酸轉(zhuǎn)移酶抗體 |
| 別 名 | Estrogen Sulfotransferase; Ste; SULT1E1; Estrogen sulfotransferase, testis isoform; Sulfotransferase, estrogen-preferring; EST; EST1; STE; sulfotransferase family 1E, estrogen-preferring, member 1; Sulfotransferase estrogen preferring; ST1E1_HUMAN. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 免疫學(xué) 生長(zhǎng)因子和激素 激酶和磷酸酶 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human, (predicted: Mouse, Rat, Dog, Pig, Horse, Rabbit, ) |
| 產(chǎn)品應(yīng)用 | WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 32kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Estrogen Sulfotranferase |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure(number and length of exons) is similar among family members. This gene encodes a protein that transfers a sulfo moiety to and from estrone, which may control levels of estrogen receptors. Function: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of estradiol and estrone. May play a role in the regulation of estrogen receptor activity by metabolizing free estradiol. Maximally sulfates beta-estradiol and estrone at concentrations of 20 nM. Also sulfates dehydroepiandrosterone, pregnenolone, ethinylestradiol, equalenin, diethylstilbesterol and 1-naphthol, at significantly higher concentrations; however, cortisol, testosterone and dopamine are not sulfated. Subunit: Homodimer. Subcellular Location: Cytoplasm. Tissue Specificity: Liver, intestine and at lower level in the kidney. Similarity: Belongs to the sulfotransferase 1 family. Database links: Entrez Gene: 6783 Human Omim: 600043 Human SwissProt: P49888 Human Unigene: 479898 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
