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Rabbit Anti-Inhibin Beta C/AP Conjugated antibody (bs-1826R-AP)
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說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢(xún)價(jià)
產(chǎn)品編號(hào) bs-1826R-AP
英文名稱(chēng) Rabbit Anti-Inhibin Beta C/AP Conjugated antibody
中文名稱(chēng) 堿性磷酸酶(AP)標(biāo)記的抑制素βC抗體
別    名 ACTIVIN BETA C; IHBC; INHBC; MGC108687; activin beta-C chain; Inhibin, beta C; inhibin beta C chain precursor; Inhbc; INHBC_HUMAN.   
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢(xún)價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  生長(zhǎng)因子和激素  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) Rat,  (predicted: Human, Mouse, Pig, Cow, Horse, )
產(chǎn)品應(yīng)用 IHC-P=1:50-200 IHC-F=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 12.5kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Inhibin Beta C
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes the beta C chain of inhibin, a member of the TGF-beta superfamily. This subunit forms heterodimers with beta A and beta B subunits. Inhibins and activins, also members of the TGF-beta superfamily, are hormones with opposing actions and are involved in hypothalamic, pituitary, and gonadal hormone secretion, as well as growth and differentiation of various cell types.

Function:
Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.

Subunit:
Homodimeric or heterodimeric through association with alpha and beta subunits, linked by one or more disulfide bonds. Inhibins are heterodimers of one alpha and one beta subunit. Activins are homo- or heterodimers of beta subunits only.

Subcellular Location:
Secreted.

Tissue Specificity:
Expressed in benign prostatic hyperplasia.

Similarity:
Belongs to the TGF-beta family.

Database links:

Entrez Gene: 3626 Human

Entrez Gene: 64549 Rat

Omim: 601233 Human

SwissProt: P55103 Human

SwissProt: Q9WUK5 Rat

Unigene: 632722 Human

Unigene: 48697 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

抑制素是轉(zhuǎn)化生長(zhǎng)因子TGFβ超級(jí)家族,主要由雌性動(dòng)物卵巢顆粒細(xì)胞和雄性動(dòng)物睪丸的Sertoli細(xì)胞分泌.研究表明,抑制素具有內(nèi)分泌和旁分泌物的作用:既可通過(guò)復(fù)雜的反饋機(jī)理,調(diào)節(jié)體液FSH水平。
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