產(chǎn)品編號 | bsm-30291M-PE |
英文名稱 | mouse H-2Dk/PE |
中文名稱 | PE標(biāo)記小鼠H-2Dk單克隆抗體 |
別 名 | HA13_MOUSE; H-2 class I histocompatibility antigen, D-K alpha chain; H-2D(K); H2-D1; |
抗體來源 | Mouse |
克隆類型 | Monoclonal |
克 隆 號 | 2A6 |
交叉反應(yīng) | |
產(chǎn)品應(yīng)用 |
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 41kDa |
性 狀 | Liquid |
亞 型 | Mouse IgG2a, k |
純化方法 | Affinity purified by Protein G |
緩 沖 液 | 0.01M PBS, 0.5%BSA, 0.03% Proclin300 |
保存條件 | Store at 2-8℃. Protect from light. Avoid freezing. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
Predicted to enable several functions, including 14-3-3 protein binding activity; TAP binding activity; and signaling receptor binding activity. Acts upstream of or within antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent; negative regulation of neuron projection development; and positive regulation of T cell mediated cytotoxicity. Located in external side of plasma membrane. Colocalizes with membrane raft. Is expressed in several structures, including alimentary system; brain; early conceptus; genitourinary system; and hemolymphoid system gland. Human ortholog(s) of this gene implicated in several diseases, including asthma (multiple); autoimmune disease (multiple); eye disease (multiple); human immunodeficiency virus infectious disease (multiple); and inner ear disease (multiple). Orthologous to several human genes including HLA-A (major histocompatibility complex, class I, A); HLA-B (major histocompatibility complex, class I, B); and HLA-C (major histocompatibility complex, class I, C). [provided by Alliance of Genome Resources, Apr 2022] SWISS: P14426 Gene ID: 14964 |
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