產(chǎn)品編號(hào) | bs-23414R |
英文名稱 | Rabbit Anti-ATP1B2 antibody |
中文名稱 | 鈉鉀ATP酶通道蛋白抗體 |
別 名 | AT1B2_HUMAN; Adhesion molecule in glia(AMOG); Sodium/potassium-dependent ATPase subunit beta-2; ATPase Na+/K+transporting subunit beta 2; |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Mouse,Rat (predicted: Human) |
產(chǎn)品應(yīng)用 | WB=1:200-1000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 33 kDa |
檢測分子量 | |
細(xì)胞定位 | 細(xì)胞膜 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human ATPase Na+/ K+ beta 2: 21-120/290 <Extracellular> |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 2 subunit. [provided by RefSeq, Jul 2008] Function: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-2 subunit is not known. Subunit: Composed of three subunits: alpha (catalytic), beta and gamma. Subcellular Location: Membrane; Single-pass type II membrane protein. Similarity: Belongs to the X(+)/potassium ATPases subunit beta family. SWISS: P14415 Gene ID: 482 Database links: Entrez Gene: 482 Human Entrez Gene: 11932 Mouse Omim: 182331 Human SwissProt: P14415 Human SwissProt: P14231 Mouse Unigene: 643540 Human Unigene: 235204 Mouse Unigene: 10624 Rat
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