產(chǎn)品編號 | bs-21198R |
英文名稱 | SLC16A12 Rabbit pAb |
中文名稱 | 溶質(zhì)載體家族16成員12抗體 |
別 名 | CJMG; DKFZp686E188; MCT 12; MCT12; Monocarboxylate transporter 12; MOT12_HUMAN; OTTHUMP00000020064; Slc16a12; Solute carrier family 16 member 12; Solute carrier family 16, member 12(monocarboxylic acid transporter 12). |
研究領(lǐng)域 | 腫瘤 細(xì)胞生物 神經(jīng)生物學(xué) 信號轉(zhuǎn)導(dǎo) 細(xì)胞膜蛋白 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human,Mouse,Pig,Cow,Dog,Horse) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 53 kDa |
檢測分子量 | |
細(xì)胞定位 | 細(xì)胞膜 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human SLC16A12: 401-486/486 <Cytoplasmic> |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
This gene encodes a transmembrane transporter that likely plays a role in monocarboxylic acid transport. A mutation in this gene has been associated with juvenile cataracts with microcornea and renal glucosuria. [provided by RefSeq, Mar 2010] Function: Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates. Subcellular Location: Cell membrane. Tissue Specificity: Most highly expressed in kidney, followed by retina, lung, and testis. Very weakly expressed in brain and liver. Also detected in lens. DISEASE: Defects in SLC16A12 are a cause of cataract juvenile with microcornea and glucosuria (CJMG) [MIM:612018]. Renal glucosuria is defined by elevated glucose level in the urine without hyperglycemia and without evidence of morphological renal anomalies. Similarity: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family. SWISS: Q6ZSM3 Gene ID: 387700 Database links: Entrez Gene: 387700 Human Entrez Gene: 240638 Mouse Omim: 611910 Human SwissProt: Q6ZSM3 Human SwissProt: Q8BGC3 Mouse Unigene: 530338 Human Unigene: 74636 Mouse |
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