| 產(chǎn)品編號(hào) | bs-21178R |
| 英文名稱 | RALGPS2 Rabbit pAb |
| 中文名稱 | RALGPS2蛋白抗體 |
| 別 名 | dJ595C2.1; FLJ10244; FLJ25604; KIAA0351; Ral A exchange factor RalGPS2; Ral GEF with PH domain and SH3 binding motif 2; RALGPS 2; ras-specific guanine nucleotide-releasing factor RalGPS2. |
| 研究領(lǐng)域 | 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) G蛋白信號(hào) |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 交叉反應(yīng) | Rat (predicted: Human,Mouse,Rabbit,Pig,Sheep,Cow,Chicken,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 65 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞漿 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human RALGPS2: 481-583/583 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
RalGPS2 (Ral GEF with PH domain and SH3 binding motif 2) is a guanine nucleotide exchange factor for RalA GTPase. It is expressed in testis and brain. Function: Guanine nucleotide exchange factor for the small GTPase RALA. May be involved in cytoskeletal organization. May also be involved in the stimulation of transcription in a Ras-independent fashion (By similarity). Subunit: Interacts with the SH3 domains of GRB2 and PLCG1. Interacts with RALA. Subcellular Location: Cell Membrane and Cytoplasmic. Associates with membranes through the PH domain. DISEASE: RALGPS2 is a potential candidate gene for susceptibility to Alzheimer disease linked to 1q24. SWISS: Q86X27 Gene ID: 55103 Database links: Entrez Gene: 424429 Chicken Entrez Gene: 457549 Chimpanzee Entrez Gene: 100052879 Horse Entrez Gene: 55103 Human Entrez Gene: 78255 Mouse Entrez Gene: 717165 Rhesus monkey Entrez Gene: 779506 Xenopus tropicalis Entrez Gene: 393446 Zebrafish SwissProt: Q5ZJK0 Chicken SwissProt: Q4R7W3 Cynomolgus Monkey SwissProt: Q86X27 Human SwissProt: Q9ERD6 Mouse Unigene: 632485 Human Unigene: 28376 Mouse Unigene: 224486 Rat |
| 產(chǎn)品圖片 |
Paraformaldehyde-fixed, paraffin embedded (rat liver tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (RALGPS2) Polyclonal Antibody, Unconjugated (bs-21178R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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