產(chǎn)品編號(hào) | bs-8006R |
英文名稱 | ZP3 Rabbit pAb |
中文名稱 | 卵母細(xì)胞透明帶糖蛋白3抗體 |
別 名 | ZP3_HUMAN; Zona pellucida sperm-binding protein 3; ZP3A; ZP3B; ZPC; Sperm receptor; ZP3A/ZP3B; Zona pellucida glycoprotein 3(Zp-3); Zona pellucida protein C; Processed zona pellucida sperm-binding protein 3; |
研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 發(fā)育生物學(xué) |
抗體來(lái)源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Cow,Horse) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 47 kDa |
檢測(cè)分子量 | |
細(xì)胞定位 | 細(xì)胞膜 分泌型蛋白 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human ZP3: 101-200/424 <Extracellular> |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
The mammalian zona pellucida, which mediates species-specific sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy, is composed of three to four glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation. Subcellular Location: Secreted > extracellular space > extracellular matrix and Cell membrane. Tissue Specificity: Oocytes. Post-translational modifications: Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida. N-glycosylated. O-glycosylated; removal of O-linked glycans may play an important role in the post-fertilization block to polyspermy. Similarity: Belongs to the ZP domain family. ZPC subfamily. Contains 1 ZP domain. SWISS: P21754 Gene ID: 7784 Database links: Entrez Gene: 511 Cow Entrez Gene: 7784 Human Omim: 182889 Human SwissProt: P21754 Human Unigene: 130553 Human Unigene: 656137 Human |
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