產(chǎn)品編號 | bs-19902R |
英文名稱 | ACTR1B Rabbit pAb |
中文名稱 | 肌動蛋白相關(guān)蛋白1B抗體 |
別 名 | Actin related protein 1B; Actin-related protein 1B; ACTR 1B; ACTY_HUMAN; ARP 1B; ARP1 actin related protein 1 homolog B; ARP1 actin related protein 1 homolog B centractin beta(yeast); ARP1 actin related protein 1 homolog B centractin beta; ARP1 actin rela |
研究領(lǐng)域 | 細(xì)胞生物 信號轉(zhuǎn)導(dǎo) 結(jié)合蛋白 細(xì)胞骨架 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Human (predicted: Mouse,Rabbit,Pig,Sheep,Cow,Dog,Horse) |
產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 42 kDa |
檢測分子量 | |
細(xì)胞定位 | 細(xì)胞漿 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human ARP1B: 301-376/376 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
This gene encodes a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related protein. These two proteins, which are of equal length and share 90% amino acid identity, are present in a constant ratio of approximately 1:15 in the dynactin complex. [provided by RefSeq, Aug 2008] Function: Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome. Subcellular Location: Cytoplasm > cytoskeleton. Cytoplasm > cytoskeleton > centrosome. Similarity: Belongs to the actin family. ARP1 subfamily. SWISS: P42025 Gene ID: 10120 Database links: Entrez Gene: 10120 Human Entrez Gene: 226977 Mouse Omim: 605144 Human SwissProt: P42025 Human SwissProt: Q8R5C5 Mouse Unigene: 98791 Human Unigene: 28521 Mouse |
產(chǎn)品圖片 | |
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