| 產(chǎn)品編號 | bs-13613R |
| 英文名稱 | LRRC6 Rabbit pAb |
| 中文名稱 | 富含亮氨酸重復蛋白6抗體 |
| 別 名 | Leucine rich repeat containing 6; Leucine rich repeat containing protein 6; Leucine rich testis specific protein; Leucine-rich repeat-containing protein 6; Leucine-rich testis-specific protein; Lrrc6; LRTP; Protein TILB homolog; Testis specific leucine rich repeat protein; Testis-specific leucine-rich repeat protein; TILB_HUMAN; TSLRP. |
| 研究領域 | 細胞生物 發(fā)育生物學 干細胞 轉(zhuǎn)錄調(diào)節(jié)因子 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應 | Human,Mouse (predicted: Rat,Pig,Sheep,Cow,Dog,Horse) |
| 產(chǎn)品應用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 54 kDa |
| 檢測分子量 | |
| 細胞定位 | 細胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human LRRC6: 201-300/466 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
The leucine-rich repeat-containing protein 6 (LRRC6), also designated Leucine-rich testis-specific protein (LRTP), is a 466 amino acid protein that contains 3 LRR repeats and plays a role in spermatogenesis. The gene encoding LRRC6 maps to chromosome 8, which encodes approximately 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and typically associated with a poor prognosis. Chromosome 8 is also associated with Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism and Waardenburg syndrome. Function: May play a role in dynein arm assembly, hence essential for proper axoneme building for cilia motility. Subcellular Location: Cytoplasm. Cell projection > cilium. Tissue Specificity: Expressed predominantly in testis and in nasal epithelial cells. DISEASE: Defects in LRRC6 are the cause of primary ciliary dyskinesia 19 (CILD19) [MIM:614935]. A disorder characterized by abnormalities of motile cilia. Respiratory infections leading to chronic inflammation and bronchiectasis are recurrent, due to defects in the respiratory cilia; reduced fertility is often observed in male patients due to abnormalities of sperm tails. Half of the patients exhibit randomization of left-right body asymmetry and situs inversus, due to dysfunction of monocilia at the embryonic node. Primary ciliary dyskinesia associated with situs inversus is referred to as Kartagener syndrome. Similarity: Belongs to the tilb protein family. Contains 1 CS domain. Contains 4 LRR (leucine-rich) repeats. Contains 1 LRRCT domain. SWISS: Q86X45 Gene ID: 23639 Database links: Entrez Gene: 23639 Human Entrez Gene: 54562 Mouse SwissProt: Q86X45 Human SwissProt: O88978 Mouse Unigene: 591865 Human Unigene: 244890 Mouse |
| 產(chǎn)品圖片 |
Sample:
Lane 1: Testis (Mouse) Lysate at 40 ug
Lane 2: A549 (Human) Cell Lysate at 30 ug
Primary: Anti-LRRC6 (bs-13613R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 54 kD
Observed band size: 54 kD
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| 1、抗體溶解方法 | |
| 2、抗體修復方式 | |
| 3、常用試劑的配制 | |
| 4、免疫組化操作步驟 | |
| 5、免疫組化問題解答 | |
| 6、Western Blotting 操作步驟 | |
| 7、Western Blotting 問題解答 | |
| 8、關(guān)于肽鏈的設計 | |
| 9、多肽的溶解與保存 | |
| 10、酶標抗體效價測定程序 | |
