| 產(chǎn)品編號(hào) | bs-12580R |
| 英文名稱 | BDP Rabbit pAb |
| 中文名稱 | 神經(jīng)母細(xì)胞瘤相關(guān)蛋白ARID3B抗體 |
| 別 名 | BDP/ARID3B; ARI3B_HUMAN; ARID domain containing protein 3B; ARID domain-containing protein 3B; Arid3b; AT rich interactive domain 3B BRIGHT like; AT rich interactive domain containing protein 3B; AT-rich interactive domain-containing protein 3B; Bright and dead ringer gene product homologous protein Bdp; Bright and dead ringer protein; Bright like; Bright-like protein; Brightlike; DRIL2. |
| 研究領(lǐng)域 | 腫瘤 發(fā)育生物學(xué) 神經(jīng)生物學(xué) 干細(xì)胞 細(xì)胞周期蛋白 表觀遺傳學(xué) |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human (predicted: Mouse,Rat,Rabbit,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 61 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human BDP/ARID3B: 251-350/561 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
ARID3B represents a member of a unique family of DNA-binding proteins that have roles in cell lineage gene regulation, cell cycle control, embryonic patterning and transcriptional regulation. ARID3B localizes to the nucleus and contains an AT-rich interactive domain (ARID) which has DNA-binding capabilities. Functioning as a transcription factor, ARID3B associates in a heterodimer with the related protein ARID3A and is believed to play an important role in neural crest survival during embryogenesis. In addition, ARID3B may participate in malignant transformation and neuroblastoma growth, suggesting a possible use of ARID3B as a tumor marker for neuroblastoma. Function: Transcription factor which may be involved in neuroblastoma growth and malignant transformation. Favors nuclear targeting of ARID3A. Subunit: Heterodimer with ARID3A. Interacts with unphosphorylated RB1. Subcellular Location: Nucleus. Tissue Specificity: Expressed in placenta, testis and leukocytes. Expressed in neuroblastoma. Present in K562 erythrocytic leukemia cells (at protein level). Similarity: Contains 1 ARID domain. Contains 1 REKLES domain. Gene ID: 10620 Database links: Entrez Gene: 56380 Mouse SwissProt: Q9Z1N7 Mouse Unigene: 425588 Mouse Unigene: 18259 Rat |
| 產(chǎn)品圖片 |
Sample:
Lane 1: K562 (Human) Cell Lysate at 30 ug
Lane 2: SH-SY5Y (Human) Cell Lysate at 30 ug
Lane 3: HepG2 (Human) Cell Lysate at 30 ug
Lane 4: Molt-4 (Human) Cell Lysate at 30 ug
Primary:
Anti-BDP (bs-12580R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 61 kD
Observed band size: 61 kD
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