| 產(chǎn)品編號 | bs-0706R |
| 英文名稱 | T4/L-Thyroxine Rabbit pAb |
| 中文名稱 | 甲狀腺素T4抗體 |
| 別 名 | Thyroxine 4; T4; Tg4; L-Thyroxine; Thyroxine; 3, 3′, 5, 5″-Tetraiodo-L-thyronine, 3-[4-(4-Hydroxy-3, 5-diiodophenoxy)-3, 5-diiodophenyl]-L-alanine. |
| 研究領(lǐng)域 | 信號轉(zhuǎn)導(dǎo) 生長因子和激素 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human) |
| 產(chǎn)品應(yīng)用 | ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 0.77687 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 分泌型蛋白 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human T4/L-Thyroxine |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Hormone produced by the thyroid glands to regulate metabolism by controlling the rate of oxidation in cells. Cases of hypothyroidism, where the gland is insufficiently active, can be treated by administration of thyroxine or a combination of thyroxine and triiodothyronine.
L-Thyroxine (T4) and triiodo-L-thyronine (T3) are iodine-containing hormones produced from thyroglobulin in the thyroid follicular cells. The stimulation of metabolic rate and regulation of growth and development by these hormones appear to be due to their effects on DNA transcription and, thus, protein synthesis. Subcellular Location: Secreted Gene ID: 51-48-9 甲狀腺素（Thyroxine, T4）是甲狀腺分泌最多的一種激素，血液中的T4全部由甲狀腺分泌而來，故血液中T4的濃度能很好地反應(yīng)甲狀腺功能狀態(tài)。正常情況下，血液中60%的T4與甲狀腺素結(jié)合球蛋白（TBG）結(jié)合，30%與甲狀腺素結(jié)合前蛋白（TBPA）結(jié)合，其余約10%與白蛋白結(jié)合，僅約0.03-0.04%呈游離狀態(tài)。由于T4與TBG親合力較高，所以血中T4的水平最易受到TBG的影響。 |
