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HAUS8 Rabbit pAb (bs-9320R)  
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產(chǎn)品編號(hào) bs-9320R
英文名稱 HAUS8 Rabbit pAb
中文名稱 HAUS8蛋白抗體
別    名 HAUS augmin like complex subunit 8; HAUS augmin-like complex subunit 8; Hec1 interacting and centrosome associated 1; HEC1/NDC80 interacting centrosome associated protein 1; HICE 1; HICE1; MGC20533; NY SAR 48; Sarcoma antigen NY SAR 48; NYS48; HAUS8_HUMAN.  
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  細(xì)胞周期蛋白  細(xì)胞分化  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human,Mouse (predicted: Rat,Dog)
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:50-200,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 45 kDa
檢測(cè)分子量
細(xì)胞定位 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 Recombinant human HAUS8 protein: 166-410/410 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 NYS48 belongs to the HAUS8 family. It is required for stabilizing spindle integrity and chromosomal integrity.

Function:
Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex.

Subunit:
Component of the HAUS augmin-like complex. The complex interacts with the gamma-tubulin ring complex and this interaction is required for spindle assembly. Associates with microtubules. The interaction with microtubules is strong during mitosis, while it is weak or absent during interphase. It is unclear whether this interaction is direct or indirect.

Subcellular Location:
Cytoplasm, cytoskeleton, Microtubule.

Similarity:
Belongs to the HAUS8 family.

SWISS:
Q9BT25

Gene ID:
93323

Database links:

Entrez Gene: 93323 Human

Omim: 613434 Human

SwissProt: Q9BT25 Human

Unigene: 404088 Human



產(chǎn)品圖片
Sample: Lane 1: Mouse Lymph node tissue lysates Lane 2: Mouse Spleen tissue lysates Primary: Anti- HAUS8 (bs-9320R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 45 kDa Observed band size: 45 kDa
Sample: Lane 1: Mouse Lymph Lysates Lane 2: Mouse SpleenLysates Lane 3: Human Jurkat cell Lysates Lane 4: Human MOLT4 cell Lysates Lane 5: Human K562 cell Lysates Primary: Anti-HAUS8 (bs-9320R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 45kDa Observed band size: 45kDa
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