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UQCRC1 Rabbit pAb (bs-8298R)  
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產品編號 bs-8298R
英文名稱 UQCRC1 Rabbit pAb
中文名稱 輔酶細胞色素C還原酶核心蛋白1抗體
別    名 Ubiquinol-Cytochrome C Reductase Core Protein I; mitochondrial; Complex III subunit 1; Core protein I; Cytochrome b c1 complex subunit 1, mitochondrial; Cytochrome b-c1 complex subunit 1; D3S3191; OTTHUMP00000164820; QCR1; QCR1_HUMAN; Ubiquinol cytochrome c reductase core protein I; Ubiquinol-cytochrome-c reductase complex core protein 1; UQCR1; UQCRC1.  
Specific References  (1)     |     bs-8298R has been referenced in 1 publications.
[IF=4] Huang Bangliang. et al. PSA controls hepatic lipid metabolism by regulating the NRF2 signaling pathway. J Mol Cell Biol. 2021 May;:  WB ;  Human.  
研究領域 細胞生物  信號轉導  線粒體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human (predicted: Mouse,Rat,Cow,Monkey,y)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 49 kDa
檢測分子量
細胞定位 細胞漿 細胞膜 線粒體
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human UQCRC1: 65-170/480 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1.

Function:
This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1.

Subunit:
The bc1 complex contains 11 subunits: 3 respiratory subunits (cytochrome b, cytochrome c1 and Rieske/UQCRFS1), 2 core proteins (UQCRC1/QCR1 and UQCRC2/QCR2) and 6 low-molecular weight proteins (UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and a cleavage product of Rieske/UQCRFS1).

Subcellular Location:
Mitochondrion inner membrane.

Post-translational modifications:
Acetylation of Lys-138 is observed in liver mitochondria from fasted mice but not from fed mice.

Similarity:
Belongs to the peptidase M16 family. UQCRC1/QCR1 subfamily.

SWISS:
Q6V1X1

Gene ID:
54878

Database links:

Entrez Gene: 54878 Human

Entrez Gene: 74388 Mouse

Entrez Gene: 315758 Rat

Omim: 606819 Human

SwissProt: Q6V1X1 Human

SwissProt: Q80YA7 Mouse

Unigene: 591106 Human

Unigene: 202749 Mouse

Unigene: 391842 Mouse



產品圖片
Tissue/cell: human lung carcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goa
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