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GPR65 Rabbit pAb (bs-7668R)  
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產(chǎn)品編號(hào) bs-7668R
英文名稱 GPR65 Rabbit pAb
中文名稱 G蛋白偶聯(lián)受體65抗體
別    名 GPCR GPR65; Dig1; G protein-coupled receptor 65; Gpcr25; GPR65; hTDAG8; Psychosine receptor; T cell death associated gene 8 protein; T-cell death-associated gene 8; TDAG8.  
Specific References  (2)     |     bs-7668R has been referenced in 2 publications.
[IF=7.396] Daichi Mori. et al. Extracellular acidity in tumor tissue upregulates programmed cell death protein?1 expression on tumor cells via proton-sensing G protein-coupled receptors. 2021 Sep 13  FC ;  mouse.  
[IF=5.193] Bortell et al. Astrocyte-specific overexpressed gene signatures in response to methamphetamine exposure in vitro. (2017) J.Neuroinflammatio. 14:49  ICC,WB ;  Rat.  
研究領(lǐng)域 細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞凋亡  細(xì)胞周期蛋白  G蛋白偶聯(lián)受體  G蛋白信號(hào)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human,Mouse,Rat
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 37 kDa
檢測分子量
細(xì)胞定位 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GPR65: 51-120/337 <Extracellular>
亞    型
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 GPR65 is a member of the G protein coupled receptor family. It has been reported in human in peripheral blood leukocytes, spleen, lymph node, and thymus. The ligand for this protein is psychosine. GPR65 may have a role in activation-induced cell death or differentiation of T cells.

Function:
Receptor for the glycosphingolipid psychosine (PSY) and several related glycosphingolipids. May have a role in activation-induced cell death or differentiation of T-cells.

Subcellular Location:
Cell membrane.

Tissue Specificity:
Predominantly expressed in thymus, spleen, lymph nodes, small intestine, lung, placenta and peripheral blood leukocytes.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

SWISS:
Q8IYL9

Gene ID:
8477

Database links:

Entrez Gene: 8477 Human

Entrez Gene: 14744 Mouse

Entrez Gene: 100155711 Pig

Entrez Gene: 299242 Rat

Omim: 604620 Human

SwissProt: Q8IYL9 Human

SwissProt: Q61038 Mouse

Unigene: 443243 Human

Unigene: 378924 Mouse



產(chǎn)品圖片
Sample: Lane 1: Lung (Mouse) Lysate at 40 ug Lane 2: Cerebrum (Mouse) Lysate at 40 ug Lane 3: Cerebrum (Rat) Lysate at 40 ug Primary: Anti-GPR65 (bs-7668R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 40 kD Observed band size: 44 kD
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