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ARL11 Rabbit pAb (bs-5987R)  
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產(chǎn)品編號 bs-5987R
英文名稱 ARL11 Rabbit pAb
中文名稱 ADP核糖基化因子樣11抗體
別    名 ADP ribosylation factor like 11; ADP ribosylation factor like protein 11; ADP ribosylation factor like tumor suppressor protein 1; ADP-ribosylation factor-like protein 11; ADP-ribosylation factor-like tumor suppressor protein 1; ARL11; ARL11_HUMAN; ARLTS1.  
Specific References  (2)     |     bs-5987R has been referenced in 2 publications.
[IF=4.46] Alexa Murray. et al. Farnesoid X receptor regulates lung macrophage activation and injury following nitrogen mustard exposure. TOXICOL APPL PHARM. 2022 Aug;:116208  IHC ;  Mouse.  
[IF=2.145] Sunil VR et al. Sarcoid-Like?Granulomatous?Disease:?Pathologic?Case?Series?in?World?Trade?Center?DustExposed?Rescue?and?Recovery?Workers.Int J Environ Res Public Health. 2019 Mar 6;16(5).  IHC-P ;  Human.  
研究領(lǐng)域 腫瘤  細胞生物  免疫學  信號轉(zhuǎn)導  G蛋白偶聯(lián)受體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse (predicted: Human,Rat,Pig,Cow)
產(chǎn)品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 21 kDa
檢測分子量
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ARL11: 65-160/196 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a tumor suppressor related to the ADP-ribosylation factor (ARF) family of proteins. The encoded protein may play a role in apoptosis in a caspase-dependent manner. Polymorphisms in this gene have been associated with some familial cancers. [provided by RefSeq, May 2010].

Function:
May play a role in apoptosis. May act as a tumor suppressor.

Tissue Specificity:
Expressed in lung and leukocytes.

DISEASE:
Defects in ARL11 may be a cause of susceptibility to chronic lymphocytic leukemia (CLL) [MIM:151400].

Similarity:
Belongs to the small GTPase superfamily. Arf family.

Gene ID:
115761

Database links:
UniProtKB/Swiss-Prot: Q969Q4.1

產(chǎn)品圖片
Tissue/cell: mouse stomach tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-ARL11 Polyclonal Antibody, Unconjugated(bs-5987R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
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