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MAP4K1 Rabbit pAb (bs-4134R)  
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產(chǎn)品編號(hào) bs-4134R
英文名稱 MAP4K1 Rabbit pAb
中文名稱 造血祖細(xì)胞激酶1抗體
別    名 Hematopoietic progenitor kinase 1; Hematopoietic progenitor kinase; HPK1; Human Hematopoietic Progenitor Kinase; M4K1_HUMAN; Map4k1; MAPK/ERK kinase kinase kinase 1; MEK kinase kinase 1; MEKKK 1; Mitogen Activated Protein Kinase Kinase Kinase Kinase 1; Mitogen-activated protein kinase kinase kinase kinase 1.  
研究領(lǐng)域 免疫學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  激酶和磷酸酶  G蛋白信號(hào)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human (predicted: Mouse,Rat,Cow)
產(chǎn)品應(yīng)用 WB=1:500-2000,Flow-Cyt=1μg/Test
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 91 kDa
檢測(cè)分子量
細(xì)胞定位 細(xì)胞漿 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MAP4K1: 231-330/833 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. May play a role in hematopoietic lineage decisions and growth regulation.

Function:
May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. May play a role in hematopoietic lineage decisions and growth regulation.

Subunit:
Interacts with MAP3K1.

Tissue Specificity:
Expressed primarily in hematopoietic organs, including bone marrow, spleen and thymus. Also expressed at very low levels in lung, kidney, mammary glands and small intestine.

Similarity:
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
Contains 1 CNH domain.
Contains 1 protein kinase domain.

SWISS:
Q92918

Gene ID:
11184

Database links:

Entrez Gene: 11184 Human

Entrez Gene: 26411 Mouse

Entrez Gene: 100516374 Pig

Entrez Gene: 292763 Rat

Omim: 601983 Human

SwissProt: Q92918 Human

SwissProt: P70218 Mouse

Unigene: 95424 Human

Unigene: 148278 Mouse



產(chǎn)品圖片
Sample: U937(Human) Cell Lysate at 30 ug Primary: Anti-MAP4K1 (bs-4134R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 91 kD Observed band size: 91 kD
Blank control: Hep G2 Cells(blue),fixed with 2% paraformaldehyde (10 min) and then permeabilized with ice-cold 90% methanol for 30 min on ice. Primary Antibody: Rabbit Anti-MAP4K1/AF647 Conjugated antibody (bs-4134R/AF647), Dilution: 1μg in 100 μL 1X PBS containing 0.5% BSA; Isotype Control Antibody: Rabbit IgG/AF647(orange) ,used under the same conditions.
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