產(chǎn)品編號 | bs-3699R |
英文名稱 | GPR15 Rabbit pAb |
中文名稱 | G蛋白偶聯(lián)受體15抗體 |
別 名 | GPCR GPR15; BOB; G protein coupled receptor 15; G protein coupled receptor GPR15; GPR15_HUMAN; G-protein coupled receptor 15; Brother of Bonzo. |
研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) 信號轉(zhuǎn)導(dǎo) G蛋白偶聯(lián)受體 細(xì)胞表面分子 G蛋白信號 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Human,Mouse,Rat (predicted: Rabbit,Dog,Horse) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:200-800
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 40 kDa |
檢測分子量 | |
細(xì)胞定位 | 細(xì)胞漿 細(xì)胞膜 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human GPR15: 51-150/360 <Extracellular> |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
This gene encodes a G protein-coupled receptor that acts as a chemokine receptor for human immunodeficiency virus type 1 and 2. The encoded protein localizes to the cell membrane. [provided by RefSeq, Nov 2012] Function: Probable chemokine receptor. Alternative coreceptor with CD4 for HIV-1 infection. Subcellular Location: Cell membrane; Multi-pass membrane protein. Similarity: Belongs to the G-protein coupled receptor 1 family. SWISS: P49685 Gene ID: 2838 Database links: Entrez Gene: 2838 Human Entrez Gene: 71223 Mouse Omim: 601166 Human SwissProt: P49685 Human SwissProt: Q0VDU3 Mouse Unigene: 563128 Human Unigene: 359970 Mouse Unigene: 426544 Mouse G蛋白偶聯(lián)受體是一種細(xì)胞表面受體,能將細(xì)胞外的分子信號傳遞至細(xì)胞內(nèi)激起細(xì)胞反應(yīng),對多種細(xì)胞行起調(diào)控作用。G蛋白偶聯(lián)受體(GPCR)參與了機(jī)體內(nèi)多種生理過程的調(diào)節(jié),是目前治療多種人類疾病包括代謝性疾病的藥物靶點(diǎn)。 |
產(chǎn)品圖片 |
Tissue/cell: Mouse stomach tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-GPR15 Polyclonal Antibody, Unconjugated(bs-3699R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
Tissue/cell: rat stomach tissue; Frozen section;
Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-GPR15 Polyclonal Antibody, Unconjugated(bs-3699R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
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